Associations of TP53 codon 72 polymorphism with complications and comorbidities in patients with type 1 diabetes

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Significant Associations of the rs3104413 Single-nucleotide Polymorphism in the HLA Region with Type 1 Diabetes

Background and Aims: In this study, the effect of rs310441 polymorphism in the human leukocyte antigen (HLA) region on the development of susceptibility or resistance to Type 1 diabetes (T1D) among the people with T1D compared to healthy subjects has been investigated. Materials and Methods: This research, which is based on the examination of 130 cases with T1D and 98 controls, has been carrie...

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Codon 72 Polymorphism of p53 Gene and Hematologic Manifestations in Patients with Systemic Lupus Erythematosus

Background: Systemic lupus erythematosus is a systemic autoimmune disorder with unclear etiology. The importance of some genes in the development of systemic lupus erythematosus has been implicated. The gene polymorphism in codon 72 has attracted a lot of attention and its role in the occurrence or progression of many cancers and autoimmune diseases especially systemic lupus erythematosus has ...

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Analysis of TP53 Codon 72 Polymorphism in Mucinous and Non-Mucinous Colorectal Adenocarcinoma in Isfahan, Iran

Background: The tumor suppressor gene TP53 (alias p53) located on chromosome 17 is involved in various cancers. Case-control studies have shown that p53 codon 72 polymorphism modulates the prognosis and susceptibility to various malignancies. We undertook the present study to explore a possible association between mucinous and non-mucinous adenocarcinomas with different genotypes or alleles at ...

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P-93: Analysis of P53 Codon 72 Gene Polymorphism in Isfahanian Patients With Endometriosis

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ژورنال

عنوان ژورنال: Journal of Molecular Medicine

سال: 2021

ISSN: 0946-2716,1432-1440

DOI: 10.1007/s00109-020-02035-1